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Title: Scintigraphic imaging of Staphylococcus aureus infection using 99mTc radiolabeled aptamers.
Title of periodic: Applied Radiation and Isotopes
Authors: Santos, Sara Roberta dos
Lacerda, Camila Maria de Sousa
Ferreira, êda Mendes
Barros, André Luís Branco de
Fernandes, Simone Odília
Cardoso, Valbert Nascimento
Andrade, Antero Silva Ribeiro de
Affiliation: Centro de Desenvolvimento da Tecnologia Nuclear, CDTN, Belo Horizonte, MG, Brasil.
Issue Date: 2017
Keywords: Aptamer;Technetium-99m;Radiopharmaceutical;Bacterial infection;Diagnosis
Abstract: Staphylococcus aureus is a specie of great medical importance associated with many infections as bacteremia and infective endocarditis as well as osteoarticular, skin and soft tissue, pleuropulmonary, and device related infections. Early identification of infectious foci is crucial for successful treatment. Scintigraphy could contribute to this purpose since specific radiotracers were available. Aptamers due to their high specificity have great potential for radiopharmaceuticals development. In the present study scintigraphic images of S. aureus infectious foci were obtained using specific S. aureus aptamers radiolabeled with 99mTc.
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Appears in Collections:Artigo de periódico

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