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Title: Novel Synthetic Compounds as Potential Anticryptococcal Agents
Title of periodic: Current Organic Synthesis
Authors: Ferreira, Soraya Maria Zandim Maciel Dias
Silva, Cleiton M. da
Fátima, Ângelo de
Freitas, Rossimiriam P.
Affiliation: Centro de Desenvolvimento da Tecnologia Nuclear, CDTN, Belo Horizonte, MG
Issue Date: 2015
Keywords: Phospholipids;Fungi;Mycoses
Abstract: Cryptococcosis, an invasive fungal infection that affects both immunocompromised and immunocompetent individuals, has emerged as an important public health problem in Africa, Asia, and America. The limited number of antimycotic drugs available to treat this disease, their side effects and toxicity, and the emergence of resistant strains support the search for more effective and less toxic compounds. This review compiles examples of novel synthetic compounds, which could be used as templates for developing novel drugs for the treatment of Cryptococcus infections.
Access: L
Appears in Collections:Artigo de periódico

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