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Title: Investigation of chemical impurities in formulation, phytotherapics and polyvitaminic medicines by k0-instrumental neutron activation analysis
Title of periodic: Nuclear Instruments and Methods in Physics Research Amsterdam
metadata.dc.title.subtitlejournal: Accellerators, Spectrometers, Detectors and Associated Equipment
Authors: Leal, Alexandre Soares
Menezes, Maria Ângela de Barros Correia
Vermaercke, L.D.
Sneyer, L.
Jensen, C.E.M.
Affiliation: Centro de Desenvolvimento da Tecnologia Nuclear/CDTN, Belo Horizonte, MG, Brasil
Centro de Desenvolvimento da Tecnologia Nuclear/CDTN, Belo Horizonte, MG, Brasil
SCK CEN Belgian Nuclear Research Centre, Mol, Belgium
SCK.CEN Belgian Nuclear Research Centre, Mol, Belgium
Centro Universitário Newton Paiva , Belo Horizonte, MG, Brasil
Issue Date: 2006
Keywords: Neutron activation analysis;drugs;medicinal plants
Abstract: In this work, comparative k0-Instrumental Neutron-Activation Analysis was performed by CDTN/CNEN/Brazil and SCK.CEN/Belgium in order to investigate the elemental concentration in samples of the same industrialised and manipulated medicine, a phytotherapic and a polyvitaminic, commonly commercialised in Brazil. The preliminary results from both Institutes are in very good agreement. Any serious contamination with possible risks to human health were found in the medicines compared with the expected values. In the case of polyvitaminic, some impurities, unexpected elements, such as La, Ti and Sm, were found in very low concentration. This first assessment confirmed the effectiveness of the k0-method in analysing such matrices.
Access: L
Appears in Collections:Artigo de periódico

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